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Seattle Genetics

Seattle GeneticsSGN-35.  Targeted antibody that identifies CD-30 and dumps a lethal dose of chemotherapy into tumor cells.

December 6, 2008 Posted by | Biotech, Companies | , , , , | Leave a comment

Whole Genome Sequencing

The standard approach in clinical DNA sequencing is that you focus on the most high impact stretches of DNA only, thereby reducing the number of base pairs that need to be sequenced.  Nonetheless, a new report to be released in todays journal Nature, discusses the whole genome sequencing of a cancer patient.

The project studied the genome of a tumor cell in a woman with acute myelogenous leukemia (AML) and compared the sequence to the genome of the same woman’s healthy skin cells.  According to the researchers, eight new mutations were identified that were specific to the patients cancer cells.

This study should invigorate the discussion surrounding whole genome sequencing and justify researchers looking to genotype entire genomes.

November 6, 2008 Posted by | Biotech | , , , | Leave a comment